For IV/IM use only
Cefoperazone + Sulbactam
Injection
Dual Support to Overcome Difficult Infections
Cefoperazone
Broad spectrum antibiotic therapy in gram +ve & -ve infections
Sulbactam
Acts as beta-lactamase inhibitor, thus restoring Cefoperazone activity against beta-lactamase producing strains
Indications
Respiratory Tract Infections
Urinary Tract Infections
Peritonitis
Cholecystitis
Cholangitis
Septicemia
Pelvic Inflammatory Diseases
Skin & Soft Tissue Inf.
Bone & Joint Inf.
Meningitis
Endometritis
Gonorrhea
Comparative Tolerability Index
The incidence of treatment-related adverse events was 6.5% and 16.4% in the cefoperazone-sulbactam and ceftazidimeamikacin-metronidazole groups, respectively, with more discontinuations due to treatment-related adverse events in the comparator arm (3.2% vs. 9.9%).
Surg Infect (Larchmt). 2008 Jun: 9(3) : 367-76
Higher Success Rates
Cefoperazone-Sulbactam has higher success rates than ceftazidime-amikacin-metronidazole (92.9% vs. 80.0%) in intra-abdominal infections.
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